Volume 2, Issue 3, June 2017, Page: 45-48
Relictual tRNAs Recognized not Chemically Inert Amino Acids, but Chemically Active Aminoacyl-Adenylates
Yuri Pivovarenko, Research and Training Center ‘Physical and Chemical Materials Science’ Under Kyiv Taras Shevchenko University and NAS of Ukraine, Kiev, Ukraine
Received: Mar. 17, 2017;       Accepted: Apr. 10, 2017;       Published: May 27, 2017
DOI: 10.11648/j.eeb.20170203.12      View  2139      Downloads  77
Abstract
Some authors believe that the genetic code originated due to the ability of amino acids to form complexes with the corresponding antikodons. We believe that it is wrong and hypothesize that the relic tRNAs did not form complexes with chemically inactive amino acids. The formation of such complexes was devoid of “biological meaning”. Instead, they recognized of chemically active forms of amino acids, namely aminoacyl-adenylates. Thus, relict recognition of amino acids, which led to the formation of the genetic code do not occur through the formation of complexes, but through a chemical reaction between the corresponding aminoacyl-adenylates and tRNAs relic. All the necessary elements of the relic of the mechanism of recognition of aminoacyl-adenylates evolutionary entrenched in the structure of modern tRNAs. The main element of such mechanism is the uridine base, which is always before the anticodons of modern sense tRNAs. Thus, thanks to our hypothesis, we can answer two fundamental questions: 1. Why only ATP activates amino acids? 2. Why only U-bases are placed before the anticodons of modern sense tRNAs?
Keywords
Genetic Code Origin, Chemical Base of the Genetic Code, Amino Acid Recognition, Amino Acids Nucleotides Relationships
To cite this article
Yuri Pivovarenko, Relictual tRNAs Recognized not Chemically Inert Amino Acids, but Chemically Active Aminoacyl-Adenylates, Ecology and Evolutionary Biology. Vol. 2, No. 3, 2017, pp. 45-48. doi: 10.11648/j.eeb.20170203.12
Copyright
Copyright © 2017 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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